Permeation of macromolecules into the renal glomerular basement membrane and capture by the tubules

How the kidney prevents urinary excretion of plasma proteins continues to be debated. Here, using unfixed whole-mount mouse kidneys, we show that fluorescent-tagged proteins and neutral dextrans permeate into the glomerular basement membrane (GBM), in general agreement with Ogston's 1958 equati...

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Detalles Bibliográficos
Autores principales: Lawrence, Marlon G., Altenburg, Michael K., Sanford, Ryan, Willett, Julian D., Bleasdale, Benjamin, Ballou, Byron, Wilder, Jennifer, Li, Feng, Miner, Jeffrey H., Berg, Ulla B., Smithies, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2017
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358373/
https://www.ncbi.nlm.nih.gov/pubmed/28246329
http://dx.doi.org/10.1073/pnas.1616457114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358373/
https://www.ncbi.nlm.nih.gov/pubmed/28246329
http://dx.doi.org/10.1073/pnas.1616457114

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