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Genome-wide transcription-coupled repair in Escherichia coli is mediated by the Mfd translocase
We used high-throughput sequencing of short, cyclobutane pyrimidine dimer-containing ssDNA oligos generated during repair of UV-induced damage to study that process at both mechanistic and systemic levels in Escherichia coli. Numerous important insights on DNA repair were obtained, bringing clarity...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358382/ https://www.ncbi.nlm.nih.gov/pubmed/28167766 http://dx.doi.org/10.1073/pnas.1700230114 |