TSG-6 Downregulates IFN-Alpha and TNF-Alpha Expression by Suppressing IRF7 Phosphorylation in Human Plasmacytoid Dendritic Cells

Proinflammatory cytokines such as TNF-α and type I interferons (IFN) are pathogenic signatures of systemic lupus erythematosus, and plasmacytoid dendritic cells (pDCs) play a major role by predominantly producing IFN-α. Given the rise of importance in identifying tumor necrosis stimulated gene 6 (TS...

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Detalles Bibliográficos
Autores principales: Kui, L., Chan, G. C., Lee, P. P. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358455/
https://www.ncbi.nlm.nih.gov/pubmed/28367002
http://dx.doi.org/10.1155/2017/7462945

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358455/
https://www.ncbi.nlm.nih.gov/pubmed/28367002
http://dx.doi.org/10.1155/2017/7462945

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