6-exo-trig Michael addition-lactonizations for catalytic enantioselective chromenone synthesis

The catalytic enantioselective 6-exo-trig Michael addition-lactonization of enone-acid substrates to form cis-chromenones with high diastereo- and enantiocontrol was developed using the commercially available isothiourea tetramisole. An acidic workup proved necessary to minimize product epimerizatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Neyyappadath, Rifahath M., Cordes, David B., Slawin, Alexandra M. Z., Smith, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358503/
https://www.ncbi.nlm.nih.gov/pubmed/28133660
http://dx.doi.org/10.1039/c6cc10178j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358503/
https://www.ncbi.nlm.nih.gov/pubmed/28133660
http://dx.doi.org/10.1039/c6cc10178j

Ejemplares similares