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TAM receptors regulate multiple features of microglial physiology

Microglia are damage sensors for the central nervous system (CNS), and the phagocytes responsible for the routine non-inflammatory clearance of dead brain cells(1). Here we show that the TAM receptor tyrosine kinases Mer and Axl(2) regulate these microglial functions. We find that mice deficient in...

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Detalles Bibliográficos
Autores principales: Fourgeaud, Lawrence, Través, Paqui G., Tufail, Yusuf, Leal-Bailey, Humberto, Lew, Erin D., Burrola, Patrick G., Callaway, Perri, Zagórska, Anna, Rothlin, Carla V., Nimmerjahn, Axel, Lemke, Greg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358512/
https://www.ncbi.nlm.nih.gov/pubmed/27049947
http://dx.doi.org/10.1038/nature17630