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The effects of exogenous lipid on THP-1 cells: an in vitro model of airway aspiration?

Chronic inflammatory diseases of the airways are associated with gastro-oesophageal reflux (GOR) and aspiration events. The observation of lipid-laden macrophages (LLMs) within the airway may indicate aspiration secondary to GOR. The proposed mechanism, that lipid droplets from undigested or partial...

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Detalles Bibliográficos
Autores principales: Hayman, Yvette A., Sadofsky, Laura R., Williamson, James D., Hart, Simon P., Morice, Alyn H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358527/
https://www.ncbi.nlm.nih.gov/pubmed/28344981
http://dx.doi.org/10.1183/23120541.00026-2016