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The effects of exogenous lipid on THP-1 cells: an in vitro model of airway aspiration?
Chronic inflammatory diseases of the airways are associated with gastro-oesophageal reflux (GOR) and aspiration events. The observation of lipid-laden macrophages (LLMs) within the airway may indicate aspiration secondary to GOR. The proposed mechanism, that lipid droplets from undigested or partial...
Autores principales: | Hayman, Yvette A., Sadofsky, Laura R., Williamson, James D., Hart, Simon P., Morice, Alyn H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Respiratory Society
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358527/ https://www.ncbi.nlm.nih.gov/pubmed/28344981 http://dx.doi.org/10.1183/23120541.00026-2016 |
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