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Optical control of AMPA receptors using a photoswitchable quinoxaline-2,3-dione antagonist
AMPA receptors respond to the neurotransmitter glutamate and play a critical role in excitatory neurotransmission. They have been implicated in several psychiatric disorders and have rich pharmacology. Antagonists of AMPA receptors have been explored as drugs and one has even reached the clinic. We...
Autores principales: | Barber, David M., Liu, Shu-An, Gottschling, Kevin, Sumser, Martin, Hollmann, Michael, Trauner, Dirk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358534/ https://www.ncbi.nlm.nih.gov/pubmed/28451208 http://dx.doi.org/10.1039/c6sc01621a |
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