Enantioselective bifunctional iminophosphorane catalyzed sulfa-Michael addition of alkyl thiols to unactivated β-substituted-α,β-unsaturated esters

The highly enantioselective sulfa-Michael addition of alkyl thiols to unactivated β-substituted-α,β-unsaturated esters catalyzed by a bifunctional iminophosphorane (BIMP) organocatalyst is described. The low acidity of the alkyl thiol pro-nucleophiles is overcome by the high Brønsted basicity of the...

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Detalles Bibliográficos
Autores principales: Yang, Jinchao, Farley, Alistair J. M., Dixon, Darren J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358540/
https://www.ncbi.nlm.nih.gov/pubmed/28451207
http://dx.doi.org/10.1039/c6sc02878k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358540/
https://www.ncbi.nlm.nih.gov/pubmed/28451207
http://dx.doi.org/10.1039/c6sc02878k

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