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SB-T-121205, a next-generation taxane, enhances apoptosis and inhibits migration/invasion in MCF-7/PTX cells

Breast cancer is the leading cause of cancer death among women. Paclitaxel, a mitotic inhibitor, is highly effective in the treatment of breast cancer. However, development of resistance to paclitaxel limits its clinical use. Identifying new compounds and new strategies that are effective against br...

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Detalles Bibliográficos
Autores principales: Zheng, Xiaowei, Wang, Changwei, Xing, Yuanming, Chen, Siying, Meng, Ti, You, Haisheng, Ojima, Iwao, Dong, Yalin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358697/
https://www.ncbi.nlm.nih.gov/pubmed/28197640
http://dx.doi.org/10.3892/ijo.2017.3871