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Ophiobolin A, a sesterpenoid fungal phytotoxin, displays different mechanisms of cell death in mammalian cells depending upon the cancer cell origin

Herein we have undertaken a systematic analysis of the effects of the fungal derivative ophiobolin A (OphA) on eight cancer cell lines from different tissue types. The LD(50) for each cell line was determined and the change in cell size determined. Flow cytometric analysis and western blotting were...

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Detalles Bibliográficos
Autores principales: Morrison, Rachel, Lodge, Tiffany, Evidente, Antonio, Kiss, Robert, Townley, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358713/
https://www.ncbi.nlm.nih.gov/pubmed/28112374
http://dx.doi.org/10.3892/ijo.2017.3858