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Ophiobolin A, a sesterpenoid fungal phytotoxin, displays different mechanisms of cell death in mammalian cells depending upon the cancer cell origin
Herein we have undertaken a systematic analysis of the effects of the fungal derivative ophiobolin A (OphA) on eight cancer cell lines from different tissue types. The LD(50) for each cell line was determined and the change in cell size determined. Flow cytometric analysis and western blotting were...
Autores principales: | Morrison, Rachel, Lodge, Tiffany, Evidente, Antonio, Kiss, Robert, Townley, Helen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358713/ https://www.ncbi.nlm.nih.gov/pubmed/28112374 http://dx.doi.org/10.3892/ijo.2017.3858 |
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