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Cbx3 maintains lineage specificity during neural differentiation

Chromobox homolog 3 (Cbx3/heterochromatin protein 1γ [HP1γ]) stimulates cell differentiation, but its mechanism is unknown. We found that Cbx3 binds to gene promoters upon differentiation of murine embryonic stem cells (ESCs) to neural progenitor cells (NPCs) and recruits the Mediator subunit Med26....

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Detalles Bibliográficos
Autores principales: Huang, Chengyang, Su, Trent, Xue, Yong, Cheng, Chen, Lay, Fides D., McKee, Robin A., Li, Meiyang, Vashisht, Ajay, Wohlschlegel, James, Novitch, Bennett G., Plath, Kathrin, Kurdistani, Siavash K., Carey, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358721/
https://www.ncbi.nlm.nih.gov/pubmed/28270516
http://dx.doi.org/10.1101/gad.292169.116