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Cbx3 maintains lineage specificity during neural differentiation
Chromobox homolog 3 (Cbx3/heterochromatin protein 1γ [HP1γ]) stimulates cell differentiation, but its mechanism is unknown. We found that Cbx3 binds to gene promoters upon differentiation of murine embryonic stem cells (ESCs) to neural progenitor cells (NPCs) and recruits the Mediator subunit Med26....
Autores principales: | Huang, Chengyang, Su, Trent, Xue, Yong, Cheng, Chen, Lay, Fides D., McKee, Robin A., Li, Meiyang, Vashisht, Ajay, Wohlschlegel, James, Novitch, Bennett G., Plath, Kathrin, Kurdistani, Siavash K., Carey, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358721/ https://www.ncbi.nlm.nih.gov/pubmed/28270516 http://dx.doi.org/10.1101/gad.292169.116 |
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