CRL2(Lrr1) promotes unloading of the vertebrate replisome from chromatin during replication termination

A key event during eukaryotic replication termination is the removal of the CMG helicase from chromatin. CMG unloading involves ubiquitylation of its Mcm7 subunit and the action of the p97 ATPase. Using a proteomic screen in Xenopus egg extracts, we identified factors that are enriched on chromatin...

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Detalles Bibliográficos
Autores principales: Dewar, James M., Low, Emily, Mann, Matthias, Räschle, Markus, Walter, Johannes C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358724/
https://www.ncbi.nlm.nih.gov/pubmed/28235849
http://dx.doi.org/10.1101/gad.291799.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358724/
https://www.ncbi.nlm.nih.gov/pubmed/28235849
http://dx.doi.org/10.1101/gad.291799.116

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