Pancreatic α- and β-cellular clocks have distinct molecular properties and impact on islet hormone secretion and gene expression

A critical role of circadian oscillators in orchestrating insulin secretion and islet gene transcription has been demonstrated recently. However, these studies focused on whole islets and did not explore the interplay between α-cell and β-cell clocks. We performed a parallel analysis of the molecula...

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Detalles Bibliográficos
Autores principales: Petrenko, Volodymyr, Saini, Camille, Giovannoni, Laurianne, Gobet, Cedric, Sage, Daniel, Unser, Michael, Heddad Masson, Mounia, Gu, Guoqiang, Bosco, Domenico, Gachon, Frédéric, Philippe, Jacques, Dibner, Charna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358758/
https://www.ncbi.nlm.nih.gov/pubmed/28275001
http://dx.doi.org/10.1101/gad.290379.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358758/
https://www.ncbi.nlm.nih.gov/pubmed/28275001
http://dx.doi.org/10.1101/gad.290379.116

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