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Streptococcus suis sortase A is Ca(2+) independent and is inhibited by acteoside, isoquercitrin and baicalin

Sortase A (SrtA) has long been recognized as an ideal drug target for therapeutic agents against Gram-positive pathogens. However, the SrtA of Streptococcus suis (Ss-SrtA), an important zoonotic agent, has not been studied. In this study, the enzymatic properties of Ss-SrtA were investigated, and in...

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Detalles Bibliográficos
Autores principales: Chen, Fuguang, Xie, Fang, Yang, Baoling, Wang, Chengcheng, Liu, Siguo, Zhang, Yueling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358767/
https://www.ncbi.nlm.nih.gov/pubmed/28319184
http://dx.doi.org/10.1371/journal.pone.0173767