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Biophysical comparison of ATP-driven proton pumping mechanisms suggests a kinetic advantage for the rotary process depending on coupling ratio
ATP-driven proton pumps, which are critical to the operation of a cell, maintain cytosolic and organellar pH levels within a narrow functional range. These pumps employ two very different mechanisms: an elaborate rotary mechanism used by V-ATPase H(+) pumps, and a simpler alternating access mechanis...
Autores principales: | Anandakrishnan, Ramu, Zuckerman, Daniel M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358804/ https://www.ncbi.nlm.nih.gov/pubmed/28319179 http://dx.doi.org/10.1371/journal.pone.0173500 |
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