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TDRD6 mediates early steps of spliceosome maturation in primary spermatocytes

Tudor containing protein 6 (TDRD6) is a male germ line-specific protein essential for chromatoid body (ChB) structure, elongated spermatid development and male fertility. Here we show that in meiotic prophase I spermatocytes TDRD6 interacts with the key protein arginine methyl transferase PRMT5, whi...

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Detalles Bibliográficos
Autores principales: Akpınar, Müge, Lesche, Mathias, Fanourgakis, Grigorios, Fu, Jun, Anasstasiadis, Konstantinos, Dahl, Andreas, Jessberger, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358835/
https://www.ncbi.nlm.nih.gov/pubmed/28263986
http://dx.doi.org/10.1371/journal.pgen.1006660