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Hepatocyte nuclear factor 1α downregulates HBV gene expression and replication by activating the NF-κB signaling pathway

The role of hepatocyte nuclear factor 1α (HNF1α) in the regulation of gene expression and replication of hepatitis B virus (HBV) is not fully understood. Previous reports have documented the induction of the expression of viral large surface protein (LHBs) by HNF1α through activating viral Sp1 promo...

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Detalles Bibliográficos
Autores principales: Lin, Junyu, Gu, Chenjian, Shen, Zhongliang, Liu, Yanfeng, Wang, Wei, Tao, Shuai, Cui, Xiaoxian, Liu, Jing, Xie, Youhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358864/
https://www.ncbi.nlm.nih.gov/pubmed/28319127
http://dx.doi.org/10.1371/journal.pone.0174017