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Simultaneous induction of Graves’ hyperthyroidism and Graves’ ophthalmopathy by TSHR genetic immunization in BALB/c mice

BACKGROUND: Graves’ disease is the most common form of autoimmune thyroid disorder, characterized by hyperthyroidism due to circulating autoantibodies. To address the pathological features and establish a therapeutic approach of this disease, an animal model carrying the phenotype of Graves’ disease...

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Detalles Bibliográficos
Autores principales: Xia, Nan, Ye, Xiaozhen, Hu, Xiaohao, Song, Shiyu, Xu, Hui, Niu, Mengyuan, Wang, Hongwei, Wang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358867/
https://www.ncbi.nlm.nih.gov/pubmed/28319174
http://dx.doi.org/10.1371/journal.pone.0174260