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Managing uncertainty in metabolic network structure and improving predictions using EnsembleFBA

Genome-scale metabolic network reconstructions (GENREs) are repositories of knowledge about the metabolic processes that occur in an organism. GENREs have been used to discover and interpret metabolic functions, and to engineer novel network structures. A major barrier preventing more widespread use...

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Detalles Bibliográficos
Autores principales: Biggs, Matthew B., Papin, Jason A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358886/
https://www.ncbi.nlm.nih.gov/pubmed/28263984
http://dx.doi.org/10.1371/journal.pcbi.1005413