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Mutation of the N-Terminal Region of Chikungunya Virus Capsid Protein: Implications for Vaccine Design
Mosquito-transmitted chikungunya virus (CHIKV) is an arthritogenic alphavirus of the Togaviridae family responsible for frequent outbreaks of arthritic disease in humans. Capsid protein, a structural protein encoded by the CHIKV RNA genome, is able to translocate to the host cell nucleolus. In encep...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358915/ https://www.ncbi.nlm.nih.gov/pubmed/28223458 http://dx.doi.org/10.1128/mBio.01970-16 |