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Inhibitors of GLUT/SLC2A Enhance the Action of BCNU and Temozolomide against High-Grade Gliomas

Glucose transport across glioblastoma membranes plays a crucial role in maintaining the enhanced glycolysis typical of high-grade gliomas and glioblastoma. We tested the ability of two inhibitors of the glucose transporters GLUT/SLC2A superfamily, indinavir (IDV) and ritonavir (RTV), and of one inhi...

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Detalles Bibliográficos
Autores principales: Azzalin, Alberto, Nato, Giulia, Parmigiani, Elena, Garello, Francesca, Buffo, Annalisa, Magrassi, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358953/
https://www.ncbi.nlm.nih.gov/pubmed/28319810
http://dx.doi.org/10.1016/j.neo.2017.02.009