Fixed-dose combination orally disintegrating tablets to treat cardiovascular disease: formulation, in vitro characterization and physiologically based pharmacokinetic modeling to assess bioavailability

Cardiovascular disease (CVD) is the leading cause of death among men and women worldwide. In CVD, hypertension and dyslipidemia commonly coexist and are managed through coadministration of amlodipine and atorvastatin, respectively. The case for fixed-dose combination (FDC) oral dosage forms and oral...

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Detalles Bibliográficos
Autores principales: Dennison, Thomas J, Smith, Julian C, Badhan, Raj K, Mohammed, Afzal R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358997/
https://www.ncbi.nlm.nih.gov/pubmed/28352156
http://dx.doi.org/10.2147/DDDT.S126035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358997/
https://www.ncbi.nlm.nih.gov/pubmed/28352156
http://dx.doi.org/10.2147/DDDT.S126035

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