Factors influencing transfection efficiency of pIDUA/nanoemulsion complexes in a mucopolysaccharidosis type I murine model

Mucopolysaccharidosis type I (MPS I) is an autosomal disease caused by alpha-l-iduronidase (IDUA) deficiency. This study used IDUA knockout mice as a model to evaluate whether parameters such as dose of plasmid and time of treatment could influence the transfection efficiency of complexes formed wit...

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Detalles Bibliográficos
Autores principales: Fraga, Michelle, de Carvalho, Talita Giacomet, Bidone, Juliana, Schuh, Roselena Silvestri, Matte, Ursula, Teixeira, Helder Ferreira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358998/
https://www.ncbi.nlm.nih.gov/pubmed/28352175
http://dx.doi.org/10.2147/IJN.S121558

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358998/
https://www.ncbi.nlm.nih.gov/pubmed/28352175
http://dx.doi.org/10.2147/IJN.S121558

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