Cargando…

PDE11A negatively regulates lithium responsivity

Lithium responsivity in patients with bipolar disorder has been genetically associated with Phosphodiesterase 11A (PDE11A), and lithium decreases PDE11A mRNA in IPSC-derived hippocampal neurons originating from lithium responsive patients. PDE11 is an enzyme uniquely enriched in the hippocampus that...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pathak, G., Agostino, M.J., Bishara, K., Capell, W.R., Fisher, J.L., Hegde, S., Ibrahim, B.A., Pilarzyk, Kaitlyn, Sabin, C., Tuczkewycz, Taras, Wilson, Steven, Kelly, M.P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359083/ https://www.ncbi.nlm.nih.gov/pubmed/27646265 http://dx.doi.org/10.1038/mp.2016.155

Ejemplares similares

Conserved age‐related increases in hippocampal PDE11A4 cause unexpected proteinopathies and cognitive decline of social associative memories
por: Pilarzyk, Katy, et al.
Publicado: (2022)

The Role of PDE11A4 in Social Isolation-Induced Changes in Intracellular Signaling and Neuroinflammation
por: Pilarzyk, Katy, et al.
Publicado: (2021)

Phosphodiesterase 11A (PDE11A), Enriched in Ventral Hippocampus Neurons, is Required for Consolidation of Social but not Nonsocial Memories in Mice
por: Hegde, Shweta, et al.
Publicado: (2016)

A genetic basis for friendship? Homophily for membrane-associated PDE11A-cAMP-CREB signaling in CA1 of hippocampus dictates mutual social preference in male and female mice
por: Smith, Abigail J., et al.
Publicado: (2021)

Activation of PDE10 and PDE11
por: Jäger, Ronald, et al.
Publicado: (2011)

Investigation of PDE5/PDE6 and PDE5/PDE11 selective potent tadalafil-like PDE5 inhibitors using combination of molecular modeling approaches, molecular fingerprint-based virtual screening protocols and structure-based pharmacophore development
por: Kayık, Gülru, et al.
Publicado: (2017)

Comparative dissolution study on counterfeit medicines of PDE-5 inhibitors
por: Deconinck, E., et al.
Publicado: (2014)

Functional characteristics and research trends of PDE11A in human diseases
por: Kong, Gyeyeong, et al.
Publicado: (2022)

Computational Study on Selective PDE9 Inhibitors on PDE9-Mg/Mg, PDE9-Zn/Mg, and PDE9-Zn/Zn Systems
por: Sivakumar, Dakshinamurthy, et al.
Publicado: (2021)

Differential Expression and Function of PDE8 and PDE4 in Effector T cells: Implications for PDE8 as a Drug Target in Inflammation
por: Vang, Amanda G., et al.
Publicado: (2016)

Association of PDE11A global haplotype with major depression and antidepressant drug response
por: Luo, Huai-Rong, et al.
Publicado: (2009)

PDE11A gene polymorphism in testicular cancer: sperm parameters and hormonal profile
por: Faja, F., et al.
Publicado: (2021)

An Overview of PDE4 Inhibitors in Clinical Trials: 2010 to Early 2022
por: Crocetti, Letizia, et al.
Publicado: (2022)

First Optimization of Novel, Potent, Selective PDE11A4 Inhibitors for Age-Related Cognitive Decline
por: Mahmood, Shams ul, et al.
Publicado: (2023)

Geometric methods in PDE’s
por: Citti, Giovanna, et al.
Publicado: (2015)

Optimization with PDE constraints
por: Pinnau, Rene, et al.
Publicado: (2008)

PDE3 is the major cGMP-PDE in adult mouse ventricular cardiomyocytes
por: Götz, Konrad R, et al.
Publicado: (2013)

PDE4 Inhibitors: Profiling Hits through the Multitude of Structural Classes
por: Jin, Jian, et al.
Publicado: (2023)

Cigarette smoke up‐regulates PDE3 and PDE4 to decrease cAMP in airway cells
por: Zuo, Haoxiao, et al.
Publicado: (2018)

Role of Phosphodiesterase 7 (PDE7) in T Cell Activity. Effects of Selective PDE7 Inhibitors and Dual PDE4/7 Inhibitors on T Cell Functions
por: Szczypka, Marianna
Publicado: (2020)

Reversal of neurobehavioral social deficits in dystrophic mice using inhibitors of phosphodiesterases PDE5A and PDE9A
por: Alexander, M S, et al.
Publicado: (2016)

Frontiers in PDE-constrained optimization
por: Antil, Harbir, et al.
Publicado: (2018)

Numerical PDE-constrained optimization
por: De los Reyes, Juan Carlos
Publicado: (2015)

Trends in PDE constrained optimization
por: Leugering, Günter, et al.
Publicado: (2014)

Pseudodifferential operators and nonlinear PDE
por: Taylor, Michael E
Publicado: (1991)

Control and optimization with PDE constraints
por: Bredies, Kristian, et al.
Publicado: (2013)

Central serous chorioretinopathy treatment with a systemic PDE5 and PDE6 inhibitor (sildenafil)
por: Coleman, D. Jackson, et al.
Publicado: (2020)

A Yeast-Based Chemical Screen Identifies a PDE Inhibitor That Elevates Steroidogenesis in Mouse Leydig Cells via PDE8 and PDE4 Inhibition
por: Demirbas, Didem, et al.
Publicado: (2013)

PDE4D and PDE4B Function in Distinct Subcellular Compartments in Mouse Embryonic Fibroblasts
por: Blackman, Brigitte E., et al.
Publicado: (2011)

Imaging of PDE2- and PDE3-Mediated cGMP-to-cAMP Cross-Talk in Cardiomyocytes
por: Pavlaki, Nikoleta, et al.
Publicado: (2018)

Experimental and theoretical evidence of dihydrogen bonds in lithium amidoborane
por: Magos-Palasyuk, Ewelina, et al.
Publicado: (2020)

Exome sequencing revealed PDE11A as a novel candidate gene for early-onset Alzheimer’s disease
por: Qin, Wei, et al.
Publicado: (2021)

Large-scale pde-constrained optimization
por: Biegler, Lorenz, et al.
Publicado: (2003)

PDE5 says NO to cGMP
por: LeBrasseur, Nicole
Publicado: (2003)

Geometric asymptotics for nonlinear PDE I
por: Maslov, V P, et al.
Publicado: (2001)

Evaluation of PDE4 inhibition for COPD
por: Wang, Desuo, et al.
Publicado: (2006)

Molecule of the month, PDE4DIP
por: Shapshak, Paul
Publicado: (2012)

Treating COPD with PDE 4 inhibitors
por: Brown, William M
Publicado: (2007)

Geometric Properties for Parabolic and Elliptic PDE's
por: Magnanini, Rolando, et al.
Publicado: (2013)

PDE and Martingale Methods in Option Pricing
por: Pascucci, Andrea
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_f4vle3cvgpq53lk6vvut22mq5s