Deletional tolerance prevents AQP4‐directed autoimmunity in mice

Neuromyelitis optica (NMO) is an autoimmune disorder of the central nervous system (CNS) mediated by antibodies to the water channel protein AQP4 expressed in astrocytes. The contribution of AQP4‐specific T cells to the class switch recombination of pathogenic AQP4‐specific antibodies and the inflam...

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Detalles Bibliográficos
Autores principales: Vogel, Anna‐Lena, Knier, Benjamin, Lammens, Katja, Kalluri, Sudhakar Reddy, Kuhlmann, Tanja, Bennett, Jeffrey L., Korn, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Highlights
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359142/
https://www.ncbi.nlm.nih.gov/pubmed/28058717
http://dx.doi.org/10.1002/eji.201646855

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359142/
https://www.ncbi.nlm.nih.gov/pubmed/28058717
http://dx.doi.org/10.1002/eji.201646855

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