Adenosine A(2A) Receptor Gene Knockout Prevents l-3,4-Dihydroxyphenylalanine-Induced Dyskinesia by Downregulation of Striatal GAD67 in 6-OHDA-Lesioned Parkinson’s Mice

l-3,4-Dihydroxyphenylalanine (l-DOPA) remains the primary pharmacological agent for the symptomatic treatment of Parkinson’s disease (PD). However, the development of l-DOPA-induced dyskinesia (LID) limits the long-term use of l-DOPA for PD patients. Some data have reported that adenosine A(2A) rece...

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Detalles Bibliográficos
Autores principales: Yin, Su-bing, Zhang, Xiao-guang, Chen, Shuang, Yang, Wen-ting, Zheng, Xia-wei, Zheng, Guo-qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359221/
https://www.ncbi.nlm.nih.gov/pubmed/28377741
http://dx.doi.org/10.3389/fneur.2017.00088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359221/
https://www.ncbi.nlm.nih.gov/pubmed/28377741
http://dx.doi.org/10.3389/fneur.2017.00088

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