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Curcumin Successfully Inhibited the Computationally Identified CYP2A6 Enzyme-Mediated Bioactivation of Aflatoxin B1 in Arbor Acres broiler

Cytochrome P450 enzymes are often responsible for the toxic and carcinogenic effects of toxicants, such as aflatoxin B1 (AFB1). The human hepatic CYP2A6 enzyme mediates the oxidative metabolism of several procarcinogens. In this study, we characterized a partial sequence of CYP2A6 gene from Arbor Ac...

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Detalles Bibliográficos
Autores principales: Muhammad, Ishfaq, Sun, Xiaoqi, Wang, He, Li, Wei, Wang, Xinghe, Cheng, Ping, Li, Sihong, Zhang, Xiuying, Hamid, Sattar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359250/
https://www.ncbi.nlm.nih.gov/pubmed/28377720
http://dx.doi.org/10.3389/fphar.2017.00143