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Computational Model of Recurrent Subthalamo-Pallidal Circuit for Generation of Parkinsonian Oscillations

Parkinson's disease is a movement disorder caused by dopamine depletion in the basal ganglia. Abnormally synchronized neuronal oscillations between 8 and 15 Hz in the basal ganglia are implicated in motor symptoms of Parkinson's disease. However, how these abnormal oscillations are generat...

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Detalles Bibliográficos
Autores principales: Shouno, Osamu, Tachibana, Yoshihisa, Nambu, Atsushi, Doya, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359256/
https://www.ncbi.nlm.nih.gov/pubmed/28377699
http://dx.doi.org/10.3389/fnana.2017.00021