Inhibition of Mammalian Target of Rapamycin (mTOR) Signaling in the Insular Cortex Alleviates Neuropathic Pain after Peripheral Nerve Injury

Injury of peripheral nerves can trigger neuropathic pain, producing allodynia and hyperalgesia via peripheral and central sensitization. Recent studies have focused on the role of the insular cortex (IC) in neuropathic pain. Because the IC is thought to store pain-related memories, translational reg...

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Detalles Bibliográficos
Autores principales: Kwon, Minjee, Han, Jeongsoo, Kim, Un Jeng, Cha, Myeounghoon, Um, Sun Woo, Bai, Sun Joon, Hong, Seong-Karp, Lee, Bae Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359287/
https://www.ncbi.nlm.nih.gov/pubmed/28377693
http://dx.doi.org/10.3389/fnmol.2017.00079