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Gut Microbiota-Dependent Metabolite Trimethylamine N-Oxide Contributes to Cardiac Dysfunction in Western Diet-Induced Obese Mice

Excessive consumption of diets high in sugars and saturated fat, frequently known as western diet (WD), may lead to obesity and metabolic syndrome. Recent evidence shows that WD-induced obesity impairs cardiac function, but the underlying mechanisms are not fully understood. Trimethylamine N-oxide (...

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Detalles Bibliográficos
Autores principales: Chen, Kui, Zheng, Xiaoqian, Feng, Mingchen, Li, Dongliang, Zhang, Hongqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359299/
https://www.ncbi.nlm.nih.gov/pubmed/28377725
http://dx.doi.org/10.3389/fphys.2017.00139