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Mechanical properties of paraformaldehyde-treated individual cells investigated by atomic force microscopy and scanning ion conductance microscopy

BACKGROUND: Cell fixation is an essential step to preserve cell samples for a wide range of biological assays involving histochemical and cytochemical analysis. Paraformaldehyde (PFA) has been widely used as a cross-linking fixation agent. It has been empirically recognized in a gold standard protoc...

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Detalles Bibliográficos
Autores principales: Kim, Seong-Oh, Kim, Joonhui, Okajima, Takaharu, Cho, Nam-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359366/
https://www.ncbi.nlm.nih.gov/pubmed/28386525
http://dx.doi.org/10.1186/s40580-017-0099-9