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Selection and Prioritization of Candidate Drug Targets for Amyotrophic Lateral Sclerosis Through a Meta-Analysis Approach

Amyotrophic lateral sclerosis (ALS) is a progressive and incurable neurodegenerative disease. Although several compounds have shown promising results in preclinical studies, their translation into clinical trials has failed. This clinical failure is likely due to the inadequacy of the animal models...

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Detalles Bibliográficos
Autores principales: Morello, Giovanna, Spampinato, Antonio Gianmaria, Conforti, Francesca Luisa, D’Agata, Velia, Cavallaro, Sebastiano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359376/
https://www.ncbi.nlm.nih.gov/pubmed/28236105
http://dx.doi.org/10.1007/s12031-017-0898-9