A Two-Tiered Mechanism Enables Localized Cdc42 Signaling during Enterocyte Polarization

Signaling by the small GTPase Cdc42 governs a diverse set of cellular processes that contribute to tissue morphogenesis. Since these processes often require highly localized signaling, Cdc42 activity must be clustered in order to prevent ectopic signaling. During cell polarization, apical Cdc42 sign...

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Detalles Bibliográficos
Autores principales: Bruurs, Lucas J. M., Zwakenberg, Susan, van der Net, Mirjam C., Zwartkruis, Fried J., Bos, Johannes L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359428/
https://www.ncbi.nlm.nih.gov/pubmed/28069739
http://dx.doi.org/10.1128/MCB.00547-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359428/
https://www.ncbi.nlm.nih.gov/pubmed/28069739
http://dx.doi.org/10.1128/MCB.00547-16

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