Spermidine Oxidation-Mediated Degeneration of Retinal Pigment Epithelium in Rats

Retinal pigment epithelium (RPE) degeneration is a crucial event in dry age-related macular degeneration and gyrate atrophy. The polyamine spermidine has been shown to induce RPE cell death in vitro. The present study aimed to establish a novel in vivo model of spermidine-induced RPE degeneration an...

Descripción completa

Detalles Bibliográficos
Autores principales: Ohashi, Koji, Kageyama, Masaaki, Shinomiya, Katsuhiko, Fujita-Koyama, Yukie, Hirai, Shin-ichiro, Katsuta, Osamu, Nakamura, Masatsugu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359532/
https://www.ncbi.nlm.nih.gov/pubmed/28367269
http://dx.doi.org/10.1155/2017/4128061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359532/
https://www.ncbi.nlm.nih.gov/pubmed/28367269
http://dx.doi.org/10.1155/2017/4128061

Ejemplares similares