Therapy targeted to the metastatic niche is effective in a model of stage IV breast cancer

Treatment of stage IV metastatic breast cancer patients is limited to palliative options and represents an unmet clinical need. Here, we demonstrate that pharmacological inhibition of miRNA-10b - a master regulator of metastatic cell viability – leads to elimination of distant metastases in a mouse...

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Detalles Bibliográficos
Autores principales: Yoo, Byunghee, Kavishwar, Amol, Wang, Ping, Ross, Alana, Pantazopoulos, Pamela, Dudley, Michael, Moore, Anna, Medarova, Zdravka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359550/
https://www.ncbi.nlm.nih.gov/pubmed/28322342
http://dx.doi.org/10.1038/srep45060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359550/
https://www.ncbi.nlm.nih.gov/pubmed/28322342
http://dx.doi.org/10.1038/srep45060

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