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Optimising reliability of mouse performance in behavioural testing: the major role of non-aversive handling
Handling laboratory animals during test procedures is an important source of stress that may impair reliability of test responses. Picking up mice by the tail is aversive, stimulating stress and anxiety. Responses among anxious animals can be confounded further by neophobia towards novel test enviro...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359560/ https://www.ncbi.nlm.nih.gov/pubmed/28322308 http://dx.doi.org/10.1038/srep44999 |