Genetic engineering of a temperate phage-based delivery system for CRISPR/Cas9 antimicrobials against Staphylococcus aureus

Discovery of clustered, regularly interspaced, short palindromic repeats and the Cas9 RNA-guided nuclease (CRISPR/Cas9) system provides a new opportunity to create programmable gene-specific antimicrobials that are far less likely to drive resistance than conventional antibiotics. However, the pract...

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Detalles Bibliográficos
Autores principales: Park, Joo Youn, Moon, Bo Youn, Park, Juw Won, Thornton, Justin A., Park, Yong Ho, Seo, Keun Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359561/
https://www.ncbi.nlm.nih.gov/pubmed/28322317
http://dx.doi.org/10.1038/srep44929

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359561/
https://www.ncbi.nlm.nih.gov/pubmed/28322317
http://dx.doi.org/10.1038/srep44929

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