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Genetic engineering of a temperate phage-based delivery system for CRISPR/Cas9 antimicrobials against Staphylococcus aureus
Discovery of clustered, regularly interspaced, short palindromic repeats and the Cas9 RNA-guided nuclease (CRISPR/Cas9) system provides a new opportunity to create programmable gene-specific antimicrobials that are far less likely to drive resistance than conventional antibiotics. However, the pract...
Autores principales: | Park, Joo Youn, Moon, Bo Youn, Park, Juw Won, Thornton, Justin A., Park, Yong Ho, Seo, Keun Seok |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359561/ https://www.ncbi.nlm.nih.gov/pubmed/28322317 http://dx.doi.org/10.1038/srep44929 |
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