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Anti-inflammatory properties of shikonin contribute to improved early-stage diabetic retinopathy

Diabetic retinopathy (DR), a major microvascular complication of diabetes, leads to retinal vascular leakage, neuronal dysfunction, and apoptosis within the retina. In this study, we combined STZ with whole-body hypoxia (10% O(2)) for quicker induction of early-stage retinopathy in C57BL/6 mice. We...

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Detalles Bibliográficos
Autores principales: Liao, Po-Lin, Lin, Cheng-Hui, Li, Ching-Hao, Tsai, Chi-Hao, Ho, Jau-Der, Chiou, George C. Y., Kang, Jaw-Jou, Cheng, Yu-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359562/
https://www.ncbi.nlm.nih.gov/pubmed/28322323
http://dx.doi.org/10.1038/srep44985