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Anti-inflammatory properties of shikonin contribute to improved early-stage diabetic retinopathy
Diabetic retinopathy (DR), a major microvascular complication of diabetes, leads to retinal vascular leakage, neuronal dysfunction, and apoptosis within the retina. In this study, we combined STZ with whole-body hypoxia (10% O(2)) for quicker induction of early-stage retinopathy in C57BL/6 mice. We...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359562/ https://www.ncbi.nlm.nih.gov/pubmed/28322323 http://dx.doi.org/10.1038/srep44985 |