A new electro-optical approach for conductance measurement: an assay for the study of drugs acting on ligand-gated ion channels

Ligand gated ion channels are involved in many pathophysiological processes and represent a relevant, although challenging, target for drug discovery. We propose an innovative electro-optical approach to their analysis able to derive membrane conductance values from the local membrane potential chan...

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Detalles Bibliográficos
Autores principales: Menegon, A., Pitassi, S., Mazzocchi, N., Redaelli, L., Rizzetto, R., Rolland, J. F., Poli, C., Imberti, M., Lanati, A., Grohovaz, F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359596/
https://www.ncbi.nlm.nih.gov/pubmed/28322303
http://dx.doi.org/10.1038/srep44843

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359596/
https://www.ncbi.nlm.nih.gov/pubmed/28322303
http://dx.doi.org/10.1038/srep44843

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