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A new electro-optical approach for conductance measurement: an assay for the study of drugs acting on ligand-gated ion channels
Ligand gated ion channels are involved in many pathophysiological processes and represent a relevant, although challenging, target for drug discovery. We propose an innovative electro-optical approach to their analysis able to derive membrane conductance values from the local membrane potential chan...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359596/ https://www.ncbi.nlm.nih.gov/pubmed/28322303 http://dx.doi.org/10.1038/srep44843 |