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Development of the Nonobese Diabetic Mouse and Contribution of Animal Models for Understanding Type 1 Diabetes
In 1974, the discovery of a mouse and a rat that spontaneously developed hyperglycemia led to the development of 2 autoimmune diabetes models: nonobese diabetic (NOD) mouse and Bio-Breeding rat. These models have contributed to our understanding of autoimmune diabetes, provided tools to dissect auto...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Lippincott Williams & Wilkins
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359790/ https://www.ncbi.nlm.nih.gov/pubmed/28291161 http://dx.doi.org/10.1097/MPA.0000000000000828 |