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B cell epitope of human cytomegalovirus phosphoprotein 65 (HCMV pp65) induced anti-dsDNA antibody in BALB/c mice

BACKGROUND: HCMV phosphoprotein 65 (HCMVpp65) is a putative immunogen that acts as an accelerator, inducing autoantibody and exacerbating autoimmune response in susceptible animals. The immunity to pp65(336-439) instigates autoimmunity, suggesting that pp65(336-439) contains crucial B cell epitope(s...

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Detalles Bibliográficos
Autores principales: HoHsieh, Ao, Wang, Chin Man, Wu, Yeong-Jian Jan, Chen, Albert, Chang, Ming-I, Chen, Ji-Yih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359867/
https://www.ncbi.nlm.nih.gov/pubmed/28320458
http://dx.doi.org/10.1186/s13075-017-1268-2