Chrysin inhibited tumor glycolysis and induced apoptosis in hepatocellular carcinoma by targeting hexokinase-2

BACKGROUND: Hexokinase-2(HK-2) plays dual roles in glucose metabolism and mediation of cell apoptosis, making it an attractive target for cancer therapy. Chrysin is a natural flavone found in plant extracts which are widely used as herb medicine in China. In the present study, we investigated the an...

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Detalles Bibliográficos
Autores principales: Xu, Dong, Jin, Junzhe, Yu, Hao, Zhao, Zheming, Ma, Dongyan, Zhang, Chundong, Jiang, Honglei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359903/
https://www.ncbi.nlm.nih.gov/pubmed/28320429
http://dx.doi.org/10.1186/s13046-017-0514-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359903/
https://www.ncbi.nlm.nih.gov/pubmed/28320429
http://dx.doi.org/10.1186/s13046-017-0514-4

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