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The effect of intra-articular botulinum toxin A on substance P, prostaglandin E(2), and tumor necrosis factor alpha in the canine osteoarthritic joint
BACKGROUND: Recently, intra-articular botulinum toxin A (IA BoNT A) has been shown to reduce joint pain in osteoarthritic dogs. Similar results have been reported in human patients with arthritis. However, the mechanism of the antinociceptive action of IA BoNT A is currently not known. The aim of th...
Autores principales: | Heikkilä, Helka M., Hielm-Björkman, Anna K., Innes, John F., Laitinen-Vapaavuori, Outi M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359943/ https://www.ncbi.nlm.nih.gov/pubmed/28327134 http://dx.doi.org/10.1186/s12917-017-0990-y |
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