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Current approaches to increase CAR T cell potency in solid tumors: targeting the tumor microenvironment
Chimeric antigen receptor (CAR) T-cell therapy represents a revolutionary treatment for haematological malignancies (i.e. B-ALL). However, the success of this type of treatment has not yet been achieved in solid tumors. One hypothesis is that the immunosuppressive nature of the tumor microenvironmen...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359946/ https://www.ncbi.nlm.nih.gov/pubmed/28331617 http://dx.doi.org/10.1186/s40425-017-0230-9 |